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run-signal-consensus-to-action

station__microgram__run-signal-consensus-to-action external (needs EXECUTION_BACKEND_URL) microgram pv-core Constructa Configa

End-to-end chain: 4-measure disproportionality consensus → signal-to-causality routing → Naranjo causality assessment → regulatory action with ICH E2B deadlines. Takes pre-computed disproportionality scores + Naranjo score + seriousness flag. Returns consensus classification, causality level, and regulatory action with deadline.

Taxonomy

Linnaean classification joined from the algovigilance taxonomy index via the parent config's rank.

Rank	Value
domain	`Substrata`
kingdom	`Constructa`
phylum	`Configa`
class	`station-config`
order	`microgram`
family	`mcp-tool-config`

Characteristics:

substrate: config
domain: pv
lifecycle: continuous
authority: read
compounding: producer
io: agent-request → tool-response

Input schema

prr numberrequired — PRR value (signal threshold: >= 2.0)
ror_ci_lower numberrequired — ROR lower 95% CI (signal threshold: > 1.0)
ic025 numberrequired — IC lower 95% credibility interval (signal threshold: > 0)
eb05 numberrequired — EBGM 5th percentile (signal threshold: > 1.0)
n_cases integerrequired — Number of reported cases (minimum 3 required)
naranjo_score integerrequired — Naranjo ADR probability score (0-13)
is_serious booleanrequired — Whether the adverse event meets ICH E2A seriousness criteria

Example call

POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__microgram__run-signal-consensus-to-action",
    "arguments": {
      "prr": 0,
      "ror_ci_lower": 0,
      "ic025": 0,
      "eb05": 0,
      "n_cases": 0,
      "naranjo_score": 0,
      "is_serious": false
    }
  }
}

How to invoke from a client

From any MCP-aware client, add https://algovigilance.com/api/mcp as an MCP server, then call this tool by name. From a raw HTTP client, send the JSON-RPC body above to /api/mcp.

Agent-friendly formats

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