# run-signal-consensus-to-action

`station__microgram__run-signal-consensus-to-action` · external (needs EXECUTION_BACKEND_URL configured) · domain `microgram` · pv-relevance `pv-core`

End-to-end chain: 4-measure disproportionality consensus → signal-to-causality routing → Naranjo causality assessment → regulatory action with ICH E2B deadlines. Takes pre-computed disproportionality scores + Naranjo score + seriousness flag. Returns consensus classification, causality level, and regulatory action with deadline.

> **Note:** This tool routes through an external execution backend. If `EXECUTION_BACKEND_URL` is unset on the server, calls return JSON-RPC error `-32603 "Tool execution backend not configured"`. Tools with `backend: native` execute in-process and are always callable.

## Agent metadata

- `idempotent`: unknown
- `read_only`: unknown
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `prr` *number* (required) — PRR value (signal threshold: >= 2.0)
- `ror_ci_lower` *number* (required) — ROR lower 95% CI (signal threshold: > 1.0)
- `ic025` *number* (required) — IC lower 95% credibility interval (signal threshold: > 0)
- `eb05` *number* (required) — EBGM 5th percentile (signal threshold: > 1.0)
- `n_cases` *integer* (required) — Number of reported cases (minimum 3 required)
- `naranjo_score` *integer* (required) — Naranjo ADR probability score (0-13)
- `is_serious` *boolean* (required) — Whether the adverse event meets ICH E2A seriousness criteria

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__microgram__run-signal-consensus-to-action",
    "arguments": {
      "prr": 0,
      "ror_ci_lower": 0,
      "ic025": 0,
      "eb05": 0,
      "n_cases": 0,
      "naranjo_score": 0,
      "is_serious": false
    }
  }
}
```

## Related

- [/tools](/tools) — all 3062 tools
- [/tools/microgram__run-signal-consensus-to-action](/tools/microgram__run-signal-consensus-to-action) — HTML page
- [/tools/microgram__run-signal-consensus-to-action/json](/tools/microgram__run-signal-consensus-to-action/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide