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run-e2a-concomitant-causality

station__microgram__run-e2a-concomitant-causality external (needs EXECUTION_BACKEND_URL) microgram pv-core Constructa Configa

ICH E2A Section II.D: Concomitant medication causality gate — determines whether a concomitant (non-suspect) drug may be contributing to the adverse event, affecting causality attribution and reporting requirements

Taxonomy

Linnaean classification joined from the algovigilance taxonomy index via the parent config's rank.

Rank	Value
domain	`Substrata`
kingdom	`Constructa`
phylum	`Configa`
class	`station-config`
order	`microgram`
family	`mcp-tool-config`

Characteristics:

substrate: config
domain: pv
lifecycle: continuous
authority: read
compounding: producer
io: agent-request → tool-response

Input schema

concomitant_drug_present booleanrequired — Input parameter: concomitant_drug_present
known_interaction booleanrequired — Input parameter: known_interaction
suspect_drug_temporal_fit booleanrequired — Input parameter: suspect_drug_temporal_fit
other_cause_identified booleanrequired — Input parameter: other_cause_identified
temporal_fit_concomitant booleanrequired — Input parameter: temporal_fit_concomitant

Example call

POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__microgram__run-e2a-concomitant-causality",
    "arguments": {
      "concomitant_drug_present": false,
      "known_interaction": false,
      "suspect_drug_temporal_fit": false,
      "other_cause_identified": false,
      "temporal_fit_concomitant": false
    }
  }
}

How to invoke from a client

From any MCP-aware client, add https://algovigilance.com/api/mcp as an MCP server, then call this tool by name. From a raw HTTP client, send the JSON-RPC body above to /api/mcp.

Agent-friendly formats

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