# run-e2a-concomitant-causality

`station__microgram__run-e2a-concomitant-causality` · external (needs EXECUTION_BACKEND_URL configured) · domain `microgram` · pv-relevance `pv-core`

ICH E2A Section II.D: Concomitant medication causality gate — determines whether a concomitant (non-suspect) drug may be contributing to the adverse event, affecting causality attribution and reporting requirements

> **Note:** This tool routes through an external execution backend. If `EXECUTION_BACKEND_URL` is unset on the server, calls return JSON-RPC error `-32603 "Tool execution backend not configured"`. Tools with `backend: native` execute in-process and are always callable.

## Agent metadata

- `idempotent`: unknown
- `read_only`: unknown
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `concomitant_drug_present` *boolean* (required) — Input parameter: concomitant_drug_present
- `known_interaction` *boolean* (required) — Input parameter: known_interaction
- `suspect_drug_temporal_fit` *boolean* (required) — Input parameter: suspect_drug_temporal_fit
- `other_cause_identified` *boolean* (required) — Input parameter: other_cause_identified
- `temporal_fit_concomitant` *boolean* (required) — Input parameter: temporal_fit_concomitant

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__microgram__run-e2a-concomitant-causality",
    "arguments": {
      "concomitant_drug_present": false,
      "known_interaction": false,
      "suspect_drug_temporal_fit": false,
      "other_cause_identified": false,
      "temporal_fit_concomitant": false
    }
  }
}
```

## Related

- [/tools](/tools) — all 3062 tools
- [/tools/microgram__run-e2a-concomitant-causality](/tools/microgram__run-e2a-concomitant-causality) — HTML page
- [/tools/microgram__run-e2a-concomitant-causality/json](/tools/microgram__run-e2a-concomitant-causality/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide