# assess-who-umc

`station__pv-engine__assess-who-umc` · external (needs EXECUTION_BACKEND_URL configured) · domain `pv-engine` · pv-relevance `pv-core`

Assess causality using the WHO-UMC system. Evaluates temporal relationship, dechallenge/rechallenge, and alternative causes to classify into 6 categories: Certain, Probable/Likely, Possible, Unlikely, Conditional/Unclassified, Unassessable/Unclassifiable. Reference: WHO-UMC Causality Assessment Guidelines.

> **Note:** This tool routes through an external execution backend. If `EXECUTION_BACKEND_URL` is unset on the server, calls return JSON-RPC error `-32603 "Tool execution backend not configured"`. Tools with `backend: native` execute in-process and are always callable.

## Agent metadata

- `idempotent`: unknown
- `read_only`: unknown
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `drug` *string* — Suspected drug name
- `event` *string* — Adverse event term
- `time_relationship` *boolean* (required) — Reasonable temporal relationship between drug and event?
- `dechallenge` *boolean* (required) — Event improved when drug stopped (positive dechallenge)?
- `rechallenge` *boolean* (required) — Event recurred when drug restarted (positive rechallenge)?
- `alternative_causes` *boolean* (required) — Can alternative causes be ruled out?
- `known_response` *boolean* — Is this a known response pattern for the drug?

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__pv-engine__assess-who-umc",
    "arguments": {
      "time_relationship": false,
      "dechallenge": false,
      "rechallenge": false,
      "alternative_causes": false
    }
  }
}
```

## Related

- [/tools](/tools) — all 3062 tools
- [/tools/pv-engine__assess-who-umc](/tools/pv-engine__assess-who-umc) — HTML page
- [/tools/pv-engine__assess-who-umc/json](/tools/pv-engine__assess-who-umc/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide