# run-perturbation-layer-classifier

`station__microgram__run-perturbation-layer-classifier` · external (needs EXECUTION_BACKEND_URL configured) · domain `microgram` · pv-relevance `pv-core`

Classifies pharmacovigilance observations into the 6-layer perturbation pattern model. Given evidence characteristics, identifies which mechanistic layer(s) the observation represents — from molecular binding (L1) through systemic feedback (L6). Exercises μ (Mapping) — each observation maps to its mechanistic origin.

> **Note:** This tool routes through an external execution backend. If `EXECUTION_BACKEND_URL` is unset on the server, calls return JSON-RPC error `-32603 "Tool execution backend not configured"`. Tools with `backend: native` execute in-process and are always callable.

## Agent metadata

- `idempotent`: unknown
- `read_only`: unknown
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `is_pathway_level` *boolean* (required) — Input parameter: is_pathway_level
- `has_mechanistic_detail` *boolean* (required) — Input parameter: has_mechanistic_detail
- `is_organ_manifestation` *boolean* (required) — Input parameter: is_organ_manifestation
- `is_functional_assay` *boolean* (required) — Input parameter: is_functional_assay
- `is_systemic_feedback` *boolean* (required) — Input parameter: is_systemic_feedback
- `evidence_source` *string* (required) — Input parameter: evidence_source
- `is_cellular_response` *boolean* (required) — Input parameter: is_cellular_response
- `is_binding_data` *boolean* (required) — Input parameter: is_binding_data

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__microgram__run-perturbation-layer-classifier",
    "arguments": {
      "is_pathway_level": false,
      "has_mechanistic_detail": false,
      "is_organ_manifestation": false,
      "is_functional_assay": false,
      "is_systemic_feedback": false,
      "evidence_source": "",
      "is_cellular_response": false,
      "is_binding_data": false
    }
  }
}
```

## Related

- [/tools](/tools) — all 3062 tools
- [/tools/microgram__run-perturbation-layer-classifier](/tools/microgram__run-perturbation-layer-classifier) — HTML page
- [/tools/microgram__run-perturbation-layer-classifier/json](/tools/microgram__run-perturbation-layer-classifier/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide