# run-epa5-signal-detect

`station__microgram__run-epa5-signal-detect` · external (needs EXECUTION_BACKEND_URL configured) · domain `microgram` · pv-relevance `pv-core`

EPA 5: Detect and validate safety signals — routes by signal strength, evidence quality, and clinical significance.

> **Note:** This tool routes through an external execution backend. If `EXECUTION_BACKEND_URL` is unset on the server, calls return JSON-RPC error `-32603 "Tool execution backend not configured"`. Tools with `backend: native` execute in-process and are always callable.

## Agent metadata

- `idempotent`: unknown
- `read_only`: unknown
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `prr` *number* (required) — Input parameter: prr
- `clinical_significance` *string* (required) — Input parameter: clinical_significance
- `case_count` *integer* (required) — Input parameter: case_count
- `has_biological_plausibility` *boolean* (required) — Input parameter: has_biological_plausibility
- `chi_squared` *number* (required) — Input parameter: chi_squared
- `has_literature_support` *boolean* (required) — Input parameter: has_literature_support

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__microgram__run-epa5-signal-detect",
    "arguments": {
      "prr": 0,
      "clinical_significance": "",
      "case_count": 0,
      "has_biological_plausibility": false,
      "chi_squared": 0,
      "has_literature_support": false
    }
  }
}
```

## Related

- [/tools](/tools) — all 3062 tools
- [/tools/microgram__run-epa5-signal-detect](/tools/microgram__run-epa5-signal-detect) — HTML page
- [/tools/microgram__run-epa5-signal-detect/json](/tools/microgram__run-epa5-signal-detect/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide