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run-dechallenge-rechallenge

station__microgram__run-dechallenge-rechallenge external (needs EXECUTION_BACKEND_URL) microgram pv-core Constructa Configa

Assess dechallenge/rechallenge evidence for drug-event causality. Positive dechallenge + positive rechallenge = STRONG evidence. ICH E2A/Naranjo criteria alignment.

Taxonomy

Linnaean classification joined from the algovigilance taxonomy index via the parent config's rank.

Rank	Value
domain	`Substrata`
kingdom	`Constructa`
phylum	`Configa`
class	`station-config`
order	`microgram`
family	`mcp-tool-config`

Characteristics:

substrate: config
domain: pv
lifecycle: continuous
authority: read
compounding: producer
io: agent-request → tool-response

Input schema

rechallenge_performed booleanrequired — Input parameter: rechallenge_performed
rechallenge_positive booleanrequired — Input parameter: rechallenge_positive
dechallenge_performed booleanrequired — Input parameter: dechallenge_performed
dechallenge_positive booleanrequired — Input parameter: dechallenge_positive

Example call

POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__microgram__run-dechallenge-rechallenge",
    "arguments": {
      "rechallenge_performed": false,
      "rechallenge_positive": false,
      "dechallenge_performed": false,
      "dechallenge_positive": false
    }
  }
}

How to invoke from a client

From any MCP-aware client, add https://algovigilance.com/api/mcp as an MCP server, then call this tool by name. From a raw HTTP client, send the JSON-RPC body above to /api/mcp.

Agent-friendly formats

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