# assess-who-umc-causality

`station__calculate__assess-who-umc-causality` · external (needs EXECUTION_BACKEND_URL configured) · domain `calculate` · pv-relevance `non-pv`

Assess drug-event causality using the WHO-UMC system. Categories: Certain, Probable/Likely, Possible, Unlikely, Conditional/Unclassified, Unassessable/Unclassifiable.

> **Note:** This tool routes through an external execution backend. If `EXECUTION_BACKEND_URL` is unset on the server, calls return JSON-RPC error `-32603 "Tool execution backend not configured"`. Tools with `backend: native` execute in-process and are always callable.

## Agent metadata

- `idempotent`: unknown
- `read_only`: unknown
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `temporal_relationship` *boolean* (required) — Is there a reasonable temporal relationship between drug and event?
- `known_response` *boolean* (required) — Is this a known response pattern to the drug?
- `dechallenge_positive` *string* (required) — Did the event improve on drug withdrawal? (yes/no/not_done)
- `rechallenge_positive` *string* (required) — Did the event recur on re-exposure? (yes/no/not_done)
- `alternative_explanation` *boolean* (required) — Could the event be explained by disease or other drugs?
- `sufficient_information` *boolean* (required) — Is there sufficient information to assess?

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__calculate__assess-who-umc-causality",
    "arguments": {
      "temporal_relationship": false,
      "known_response": false,
      "dechallenge_positive": "",
      "rechallenge_positive": "",
      "alternative_explanation": false,
      "sufficient_information": false
    }
  }
}
```

## Related

- [/tools](/tools) — all 3062 tools
- [/tools/calculate__assess-who-umc-causality](/tools/calculate__assess-who-umc-causality) — HTML page
- [/tools/calculate__assess-who-umc-causality/json](/tools/calculate__assess-who-umc-causality/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide