# assess-naranjo-causality

`station__calculate__assess-naranjo-causality` · external (needs EXECUTION_BACKEND_URL configured) · domain `calculate` · pv-relevance `non-pv`

Compute Naranjo adverse drug reaction probability score (0-13). Categories: Definite (>=9), Probable (5-8), Possible (1-4), Doubtful (<=0).

> **Note:** This tool routes through an external execution backend. If `EXECUTION_BACKEND_URL` is unset on the server, calls return JSON-RPC error `-32603 "Tool execution backend not configured"`. Tools with `backend: native` execute in-process and are always callable.

## Agent metadata

- `idempotent`: unknown
- `read_only`: unknown
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `previous_reports` *boolean* (required) — Are there previous conclusive reports on this reaction?
- `after_drug` *boolean* (required) — Did the adverse event appear after the suspected drug was administered?
- `improved_on_withdrawal` *string* (required) — Did the reaction improve when the drug was discontinued? (yes/no/not_withdrawn)
- `reappeared_on_rechallenge` *string* (required) — Did the reaction reappear on rechallenge? (yes/no/not_done)
- `alternative_causes` *boolean* (required) — Are there alternative causes that could have caused the reaction?
- `placebo_reaction` *string* (required) — Did the reaction appear when placebo was given? (yes/no/not_done)
- `drug_detected` *string* (required) — Was the drug detected in blood/fluids in toxic concentrations? (yes/no/not_done)
- `dose_related` *string* (required) — Was the reaction more severe with higher dose or less severe with lower dose? (yes/no/not_done)
- `previous_exposure` *boolean* (required) — Did the patient have a similar reaction to the same or similar drugs previously?
- `objective_evidence` *boolean* (required) — Was the adverse event confirmed by objective evidence?

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__calculate__assess-naranjo-causality",
    "arguments": {
      "previous_reports": false,
      "after_drug": false,
      "improved_on_withdrawal": "",
      "reappeared_on_rechallenge": "",
      "alternative_causes": false,
      "placebo_reaction": "",
      "drug_detected": "",
      "dose_related": "",
      "previous_exposure": false,
      "objective_evidence": false
    }
  }
}
```

## Related

- [/tools](/tools) — all 3062 tools
- [/tools/calculate__assess-naranjo-causality](/tools/calculate__assess-naranjo-causality) — HTML page
- [/tools/calculate__assess-naranjo-causality/json](/tools/calculate__assess-naranjo-causality/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide