{"mcpName":"station__algovigilance__microgram-pv-engine-assess-naranjo","slug":"algovigilance__microgram-pv-engine-assess-naranjo","label":"Microgram: pv-engine-assess-naranjo","description":"Run the Naranjo Adverse Drug Reaction Probability Scale. Scores 10 questions about temporal relationship, dechallenge, rechallenge, alternative causes, dose-response, and objective evidence. Returns total score (range -4 to +13) and category: Definite (>=9), Probable (5-8), Possible (1-4), Doubtful (<=0). Reference: Naranjo et al. (1981) Clin Pharmacol Ther 30:239-245.","domainSlug":"algovigilance","pvRelevance":"pv-core","backend":"native","agentMetadata":{"idempotent":true,"read_only":true,"expected_latency_ms":null,"cost_tokens_estimate":null,"pipes_to":null},"inputSchema":{"type":"object","properties":{"drug":{"type":"string","description":"Suspected drug name"},"event":{"type":"string","description":"Adverse event term"},"q1_previous_reports":{"type":"string","description":"Previous conclusive reports on this reaction? (yes/no/unknown)"},"q2_temporal_relationship":{"type":"string","description":"Event appeared after suspected drug was given? (yes/no/unknown)"},"q3_dechallenge":{"type":"string","description":"ADR improved when drug was discontinued? (yes/no/unknown)"},"q4_rechallenge":{"type":"string","description":"ADR reappeared when drug was readministered? (yes/no/unknown)"},"q5_alternative_causes":{"type":"string","description":"Alternative causes could explain the reaction? (yes/no/unknown)"},"q6_placebo_response":{"type":"string","description":"Reaction appeared when placebo was given? (yes/no/unknown)"},"q7_drug_concentration":{"type":"string","description":"Drug detected in blood in toxic concentration? (yes/no/unknown)"},"q8_dose_response":{"type":"string","description":"Reaction more severe with increased dose? (yes/no/unknown)"},"q9_previous_experience":{"type":"string","description":"Patient had similar reaction to same or similar drugs? (yes/no/unknown)"},"q10_objective_evidence":{"type":"string","description":"ADR confirmed by objective evidence? (yes/no/unknown)"}},"required":["q1_previous_reports","q2_temporal_relationship","q3_dechallenge","q4_rechallenge","q5_alternative_causes","q6_placebo_response","q7_drug_concentration","q8_dose_response","q9_previous_experience","q10_objective_evidence"],"additionalProperties":false},"example":null,"taxonomy":{"rank":{"domain":"Substrata","kingdom":"Constructa","phylum":"Configa","class":"station-config","order":"algovigilance","family":"mcp-tool-config"},"characteristics":{"substrate":"config","domain":"pv","lifecycle":"continuous","stateful":false,"persistence":"none","authority":"read","compounding":"producer","io_input":"agent-request","io_output":"tool-response"}},"_links":{"html":"/tools/algovigilance__microgram-pv-engine-assess-naranjo","markdown":"/tools/algovigilance__microgram-pv-engine-assess-naranjo/raw.md","invoke":"/api/mcp","catalog":"/api/mcp"}}