# Microgram: microgram-run-dechallenge-rechallenge

`station__algovigilance__microgram-microgram-run-dechallenge-rechallenge` · native (always callable) · domain `algovigilance` · pv-relevance `pv-core`

Assess dechallenge/rechallenge evidence for drug-event causality. Positive dechallenge + positive rechallenge = STRONG evidence. ICH E2A/Naranjo criteria alignment.

## Agent metadata

- `idempotent`: true
- `read_only`: true
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `rechallenge_performed` *boolean* (required) — Input parameter: rechallenge_performed
- `rechallenge_positive` *boolean* (required) — Input parameter: rechallenge_positive
- `dechallenge_performed` *boolean* (required) — Input parameter: dechallenge_performed
- `dechallenge_positive` *boolean* (required) — Input parameter: dechallenge_positive

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__algovigilance__microgram-microgram-run-dechallenge-rechallenge",
    "arguments": {
      "rechallenge_performed": false,
      "rechallenge_positive": false,
      "dechallenge_performed": false,
      "dechallenge_positive": false
    }
  }
}
```

## Related

- [/tools](/tools) — all 7718 tools
- [/tools/algovigilance__microgram-microgram-run-dechallenge-rechallenge](/tools/algovigilance__microgram-microgram-run-dechallenge-rechallenge) — HTML page
- [/tools/algovigilance__microgram-microgram-run-dechallenge-rechallenge/json](/tools/algovigilance__microgram-microgram-run-dechallenge-rechallenge/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide