# Microgram: ich-q1a-stability-testing

`station__algovigilance__microgram-ich-q1a-stability-testing` · native (always callable) · domain `algovigilance` · pv-relevance `pv-core`

ICH Q1A(R2) Stability Testing of New Drug Substances and Products. Routes stability study design based on product type, storage type, long-term condition choice, and accelerated study outcome. Covers general case, refrigerator, freezer, below -20C, impermeable containers, and semi-permeable containers. Source: ICH Q1A(R2) Step 4, 6 Feb 2003.

## Agent metadata

- `idempotent`: true
- `read_only`: true
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `product_type` *string* (required) — drug_substance or drug_product
- `storage_type` *string* (required) — general, refrigerator, freezer, below_minus_20, semi_permeable, impermeable
- `long_term_condition` *string* — For general case: 25_60 (default) or 30_65. For semi-permeable: 25_40 (default) or 30_35.
- `significant_change_accelerated` *boolean* — Whether significant change was observed during accelerated stability testing
- `significant_change_timing` *string* — within_3_months or between_3_and_6_months

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__algovigilance__microgram-ich-q1a-stability-testing",
    "arguments": {
      "product_type": "",
      "storage_type": ""
    }
  }
}
```

## Related

- [/tools](/tools) — all 7718 tools
- [/tools/algovigilance__microgram-ich-q1a-stability-testing](/tools/algovigilance__microgram-ich-q1a-stability-testing) — HTML page
- [/tools/algovigilance__microgram-ich-q1a-stability-testing/json](/tools/algovigilance__microgram-ich-q1a-stability-testing/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide