# Microgram: fda-pediatric-extrapolation

`station__algovigilance__microgram-fda-pediatric-extrapolation` · native (always callable) · domain `algovigilance` · pv-relevance `pv-core`

ICH E11A pediatric extrapolation decision tree: determines study requirements by disease similarity and PK comparability per ICH E11A 'Pediatric Extrapolation' (2024)

## Agent metadata

- `idempotent`: true
- `read_only`: true
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `disease_similar_adults` *boolean* (required) — Whether the disease course is similar in pediatric and adult populations
- `response_similar_adults` *boolean* (required) — Whether drug response is expected to be similar in pediatric and adult populations
- `pk_data_available` *boolean* — Whether adequate PK data exists in the pediatric population
- `age_group` *string* — Pediatric age group: neonate, infant, child, adolescent

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__algovigilance__microgram-fda-pediatric-extrapolation",
    "arguments": {
      "disease_similar_adults": false,
      "response_similar_adults": false
    }
  }
}
```

## Related

- [/tools](/tools) — all 7718 tools
- [/tools/algovigilance__microgram-fda-pediatric-extrapolation](/tools/algovigilance__microgram-fda-pediatric-extrapolation) — HTML page
- [/tools/algovigilance__microgram-fda-pediatric-extrapolation/json](/tools/algovigilance__microgram-fda-pediatric-extrapolation/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide