# Microgram: fda-boxed-warning-criteria

`station__algovigilance__microgram-fda-boxed-warning-criteria` · native (always callable) · domain `algovigilance` · pv-relevance `pv-core`

FDA boxed warning determination: routes by risk severity and preventability per FDA Guidance 'Warnings and Precautions, Contraindications, and Boxed Warning Sections of Labeling' (2011) and 21 CFR 201.57(c)(1)

## Agent metadata

- `idempotent`: true
- `read_only`: true
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `risk_severity` *string* (required) — Severity of the adverse reaction: fatal, life_threatening, serious_disability, serious_reversible, moderate
- `risk_preventable` *boolean* — Whether the risk is avoidable with appropriate monitoring or dose adjustment
- `risk_well_known` *boolean* — Whether the risk is well-established and clinically significant
- `restricted_distribution` *boolean* — Whether drug requires restricted distribution program

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__algovigilance__microgram-fda-boxed-warning-criteria",
    "arguments": {
      "risk_severity": ""
    }
  }
}
```

## Related

- [/tools](/tools) — all 7718 tools
- [/tools/algovigilance__microgram-fda-boxed-warning-criteria](/tools/algovigilance__microgram-fda-boxed-warning-criteria) — HTML page
- [/tools/algovigilance__microgram-fda-boxed-warning-criteria/json](/tools/algovigilance__microgram-fda-boxed-warning-criteria/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide