# Microgram: e2d-expectedness-assessment

`station__algovigilance__microgram-e2d-expectedness-assessment` · native (always callable) · domain `algovigilance` · pv-relevance `pv-core`

ICH E2D Section 2.2: Determines expectedness of a post-approval adverse drug reaction against the reference safety information (SmPC or CCDS)

## Agent metadata

- `idempotent`: true
- `read_only`: true
- `expected_latency_ms`: unknown (not yet contract-tested)
- `cost_tokens_estimate`: unknown

## Input schema

- `in_reference_text` *boolean* — Input variable in_reference_text
- `reference_document` *string* — Input variable reference_document
- `severity_matches` *boolean* — Input variable severity_matches
- `specificity_matches` *boolean* — Input variable specificity_matches
- `class_effect_only` *boolean* — Input variable class_effect_only

## Example call

```json
POST /api/mcp
Content-Type: application/json

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "station__algovigilance__microgram-e2d-expectedness-assessment",
    "arguments": {}
  }
}
```

## Related

- [/tools](/tools) — all 7718 tools
- [/tools/algovigilance__microgram-e2d-expectedness-assessment](/tools/algovigilance__microgram-e2d-expectedness-assessment) — HTML page
- [/tools/algovigilance__microgram-e2d-expectedness-assessment/json](/tools/algovigilance__microgram-e2d-expectedness-assessment/json) — JSON form (agent-friendly)
- [/api/mcp](/api/mcp) — endpoint
- [/AGENTS.md](/AGENTS.md) — agent guide